Thema: News: Cerebral Astroblastoma
News: Cerebral Astroblastoma
Tina[a]
30.05.2004 21:49:20
Acta Neurochir (Wien). 2004 Jun;146(6):629-33. Epub 2004 Apr 13
Cerebral astroblastoma.
Caroli E, Salvati M, Esposito V, Orlando ER, Giangaspero F.
Ospedale S. Andrea, Department of Neurosurgery, University of Rome "La Sapienza", Rome, Italy.
Background. Astroblastoma is a rare glial tumour about which little is known. Method. We report a case of cerebral high grade astroblastoma and discuss the clinical, histopathological, surgical, radiological and prognostic features of this tumour, in the light of the pertinent literature. Result. Present patient had an initial histological diagnosis of glioblastoma multiforme. Three years later an histological revaluation was performed and revealed a high grade astroblastoma. Our patient underwent surgical removal and radiotherapy; five years after the operation he is alive and without evidence of recurrence. Interpretation. Classification and histogenesis of this tumour is still debated. The lack of a clinicopathological correlation makes the prognosis of this tumour unpredictable. The optimal management is not defined, but total resection and post-operative radiotherapy seem to be the effective means to treat the astroblastoma.
Cerebral astroblastoma.
Caroli E, Salvati M, Esposito V, Orlando ER, Giangaspero F.
Ospedale S. Andrea, Department of Neurosurgery, University of Rome "La Sapienza", Rome, Italy.
Background. Astroblastoma is a rare glial tumour about which little is known. Method. We report a case of cerebral high grade astroblastoma and discuss the clinical, histopathological, surgical, radiological and prognostic features of this tumour, in the light of the pertinent literature. Result. Present patient had an initial histological diagnosis of glioblastoma multiforme. Three years later an histological revaluation was performed and revealed a high grade astroblastoma. Our patient underwent surgical removal and radiotherapy; five years after the operation he is alive and without evidence of recurrence. Interpretation. Classification and histogenesis of this tumour is still debated. The lack of a clinicopathological correlation makes the prognosis of this tumour unpredictable. The optimal management is not defined, but total resection and post-operative radiotherapy seem to be the effective means to treat the astroblastoma.
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