Thema: Presse: Fathers pollutant exposure ups kids brain tumor risk
Presse: Fathers pollutant exposure ups kids brain tumor risk
Frank[a]
14.07.2004 18:52:31
Fathers´ pollutant exposure ups kids´ brain tumor risk
Children fathered by men who have been exposed to polycyclic aromatic hydrocarbons (PAH) apparently have increased odds of developing brain tumors, researchers report
"Experimental evidence suggests that parental exposure to PAH, which occurs primarily through tobacco smoke, occupational exposure, and air pollution, could increase the risk of cancer during childhood," Dr. Sylvaine Cordier of Institut National de la Sante et de la Recherche Medicale, in Rennes, France, and colleagues explain in the American Journal of Epidemiology.
To see if this was true in real life, the researchers used data from population-based studies carried out in seven countries. They compare data from 1218 cases of childhood brain tumor and 2223 matched "control" children without cancer.
Occupational data were used to estimate parental PAH exposure during the 5 years before the children´s birth.
Paternal occupational PAH exposure increased the odds a child developing any type of brain tumor by 30 percent. No evidence of an increase in risk was seen with increasing levels of exposure.
Compared with non-smoking, non-occupationally exposed fathers, paternal smoking alone increased the odds of childhood brain tumors by 10%.
Maternal occupational exposure to PAH during pregnancy was rare, according to the investigators, and no significant association was found between maternal occupational exposure and any type of childhood brain tumor.
Reuters
July 12, 2004
Children fathered by men who have been exposed to polycyclic aromatic hydrocarbons (PAH) apparently have increased odds of developing brain tumors, researchers report
"Experimental evidence suggests that parental exposure to PAH, which occurs primarily through tobacco smoke, occupational exposure, and air pollution, could increase the risk of cancer during childhood," Dr. Sylvaine Cordier of Institut National de la Sante et de la Recherche Medicale, in Rennes, France, and colleagues explain in the American Journal of Epidemiology.
To see if this was true in real life, the researchers used data from population-based studies carried out in seven countries. They compare data from 1218 cases of childhood brain tumor and 2223 matched "control" children without cancer.
Occupational data were used to estimate parental PAH exposure during the 5 years before the children´s birth.
Paternal occupational PAH exposure increased the odds a child developing any type of brain tumor by 30 percent. No evidence of an increase in risk was seen with increasing levels of exposure.
Compared with non-smoking, non-occupationally exposed fathers, paternal smoking alone increased the odds of childhood brain tumors by 10%.
Maternal occupational exposure to PAH during pregnancy was rare, according to the investigators, and no significant association was found between maternal occupational exposure and any type of childhood brain tumor.
Reuters
July 12, 2004
Frank[a]
